Nucleoside/Sugar Chemistry

SreeGana Pharma Scientific team have experienced in Modification of Nucleoside bases, Metal Mediating Reactions on Nucleosides (Suzuki, Sonogashira, Heck, Kumada, Stille, Carbonylation and Buchwald couplings) Modification of Sugar Moieties, Alkylation, Fluorination Reaction at Nucleosides Based and Sugar Moieties.

• Development of novel methodologies for the synthesis of modified nucleobases and nucleosides.
• Medicinal chemistry of analogues of nucleobases and nucleosides.
• Design and synthesis of novel C-nucleosides for chemical biology.
• Synthesis of modified nucleoside triphosphates .
• Novel fluorescent DNA labeling for bioanalytical applications.
• Chemical biology of base-modified nucleic acids.
• Click Reaction Applications in Nucelobases.